Five isoflavone glycosides, named derriscandenosides A-E (1-5), were isolated from the stems of Derris scandens, together with ten known compounds comprising one isoflavone, two benzoic acid derivatives, three glucosyl isoflavones and four rhamnosyl-(1-->6)-glucosyl isoflavones. The structures of the glycosides were assigned on the basis of spectroscopic data, especially of the acetate derivatives. Three known rhamnosyl-(1-->6)-glucosyl isoflavones isolated from a crude fraction were retested for hypotensive activity with varying results.