Does asbestos exposure cause non-Hodgkin's lymphoma or related hematolymphoid cancers? A review of the epidemiologic literature

Clin Lymphoma. 2002 Jun;3(1):36-40. doi: 10.3816/clm.2002.n.009.

Abstract

Asbestos exposure has been linked to non-Hodgkin's lymphoma (NHL) and other types of hematolymphoid cancer (HL-CA) in several case reports and epidemiologic studies. This review covers the scientific and medical literature on the issue of whether asbestos exposure is a cause of NHL or other HL-CAs. Studies of animals exposed to asbestos have not shown an increase in NHL or other types of HL-CA. Although some patients with asbestosis have mild immunologic abnormalities, 32 of 35 epidemiologic studies of asbestos exposure in humans are negative for NHL or other HL-CAs. Therefore, it can be concluded that there is no increased risk of NHL or other HL-CAs associated with asbestos exposure.

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Adult
  • Asbestos / adverse effects*
  • Asbestos, Crocidolite / adverse effects
  • Asbestosis / complications
  • Asbestosis / epidemiology
  • Case-Control Studies
  • Cohort Studies
  • Construction Materials
  • Environmental Exposure
  • Female
  • Hematologic Neoplasms / epidemiology
  • Hematologic Neoplasms / etiology*
  • Humans
  • Leukemia / epidemiology
  • Leukemia / etiology
  • Lymphoma, Non-Hodgkin / epidemiology
  • Lymphoma, Non-Hodgkin / etiology*
  • Male
  • Metallurgy
  • Mining
  • Occupational Diseases / epidemiology
  • Occupational Diseases / etiology
  • Occupational Exposure
  • Risk
  • Transportation

Substances

  • Asbestos, Crocidolite
  • Asbestos