Abstract
Experimental data on the comparative study of the invasive properties of vct+ Hly- and vct- Hly+ V. cholerae of serogroups 01 and 0139 are presented. Both vct- Hly+ and vct+ Hly- V. cholerae of serogroups 01 and 0139 have been shown to be capable of dissemination into internal organs. No differences in the dissemination of V. cholerae of different serogroups in both immunologically immature and mature experimental animals have been detected.
MeSH terms
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Animals
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Animals, Suckling
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Bacterial Proteins / genetics
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Cholera / immunology
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Cholera / microbiology*
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Disease Models, Animal
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Guinea Pigs
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Hemolysin Proteins / genetics
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Rabbits
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Receptors, Cell Surface / deficiency
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Receptors, Cell Surface / genetics
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Vibrio cholerae* / genetics
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Vibrio cholerae* / isolation & purification
Substances
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Bacterial Proteins
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Hemolysin Proteins
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Receptors, Cell Surface
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VctA protein, Vibrio cholerae
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hlyA protein, Vibrio cholerae