Two cases of polymorphic ventricular tachycardia induced by the administration of verapamil against paroxysmal supraventricular tachycardia

Intern Med. 2002 Jun;41(6):445-8. doi: 10.2169/internalmedicine.41.445.

Abstract

Verapamil is widely used for the termination of paroxysmal supraventricular tachycardia (PSVT) with little proarrhythmic effect. We describe two cases of PSVT that changed to non-sustained polymorphic ventricular tachycardia after administration of verapamil. Electrophysiological study revealed atrioventricular nodal reentrant tachycardia in the first case, and atrioventricular reentrant tachycardia due to a concealed left lateral accessory pathway in the second case. Catecholamine-induced automaticity was one of the possible mechanisms of VT in the first case, but the mechanism is unknown in the second case.

Publication types

  • Case Reports

MeSH terms

  • Anti-Arrhythmia Agents / adverse effects*
  • Catheter Ablation
  • Electrocardiography
  • Electrophysiologic Techniques, Cardiac
  • Female
  • Humans
  • Male
  • Middle Aged
  • Tachycardia, Supraventricular / drug therapy*
  • Tachycardia, Ventricular / chemically induced*
  • Treatment Outcome
  • Verapamil / adverse effects*

Substances

  • Anti-Arrhythmia Agents
  • Verapamil