Objective: To evaluate the feasibility and effect of treatment of thyroid adenoma and cystic degeneration of thyroid adenoma by injection of colloid (32)P with ultrasonic guidance.
Methods: Diluted solutions of (32)P, 37 approximately 74 mBq/1.0 approximately 1.5 ml and 18.5 approximately 37 mBq/ml, were injected, with ultrasonic guidance, into the thyroid adenoma in 30 cases and degenerated cyst of thyroid adenoma in 30 cases, all confirmed by ultrasonography, thyroid scanning and pathologic paracentesis. The serum FT3, FT4, TT3, TT4, and TSH, and blood cells were examined before and after the treatment. Part of the patients was followed up for 6 approximately 36 months.
Results: The cure rate was 71.05% (27/38) for thyroid adenoma and 86.67% (26/30) for cystic degeneration of thyroid adenoma. The treatment effect was better for cystic degeneration of thyroid adenoma than for thyroid adenoma. The changes of blood cells and serum thyroid hormones were not significant before and after treatment. No obvious side effect was found in all patients.
Conclusion: Injection of (32)P with ultrasonic guidance is effective in treatment of thyroid adenoma and cystic degeneration of thyroid adenoma. This method is easy, safe and highly practical clinically.