Choanal atresia: the result of maternal thyrotoxicosis or fetal carbimazole?

Am J Med Genet. 2002 Jul 22;111(1):55-6; discussion 54. doi: 10.1002/ajmg.10458.

Abstract

We present the fourth published case of a child affected with choanal atresia following maternal treatment with carbimazole. The mother was receiving her highest dose of carbimazole at the crucial period for development of the choanae, between days 35 and 38.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Antithyroid Agents / adverse effects*
  • Carbimazole / adverse effects*
  • Choanal Atresia / chemically induced
  • Choanal Atresia / etiology*
  • Female
  • Fever / etiology
  • Humans
  • Infant, Low Birth Weight
  • Infant, Newborn
  • Male
  • Microcephaly / chemically induced
  • Microcephaly / etiology
  • Pregnancy
  • Pregnancy Complications / drug therapy*
  • Thyrotoxicosis / drug therapy*

Substances

  • Antithyroid Agents
  • Carbimazole