First examples of the catalytic asymmetric ring-opening of meso 1,2-dioxines utilising cobalt(II) complexes with optically active tetradentate Schiff base ligands: formation of enantio-enriched cyclopropanes

Thomas D Avery; Natalie F Jenkins; Marc C Kimber; David W Lupton; Dennis K Taylor

doi:10.1039/b109187p

First examples of the catalytic asymmetric ring-opening of meso 1,2-dioxines utilising cobalt(II) complexes with optically active tetradentate Schiff base ligands: formation of enantio-enriched cyclopropanes

Chem Commun (Camb). 2002 Jan 7:(1):28-9. doi: 10.1039/b109187p.

Authors

Thomas D Avery¹, Natalie F Jenkins, Marc C Kimber, David W Lupton, Dennis K Taylor

Affiliation

¹ Department of Chemistry, Adelaide University, South Australia, Australia, 5005.

PMID: 12120294
DOI: 10.1039/b109187p

Abstract

The combination of chiral cobalt beta-ketoiminato or cobalt salen complexes and meso 1,2-dioxines leads to catalytic asymmetric ring-opening affording enantio-enriched cis gamma-hydroxy enones; subsequent capture by an ylide affords enantio-enriched cyclopropanes.