The fluorine gauche effect. Langmuir isotherms report the relative conformational stability of (+/-)-erythro- and (+/-)-threo-9,10-difluorostearic acids

Mustafa Tavasli; David O'Hagan; Christopher Pearson; Michael C Petty

doi:10.1039/b202891c

The fluorine gauche effect. Langmuir isotherms report the relative conformational stability of (+/-)-erythro- and (+/-)-threo-9,10-difluorostearic acids

Chem Commun (Camb). 2002 Jun 7:(11):1226-7. doi: 10.1039/b202891c.

Authors

Mustafa Tavasli¹, David O'Hagan, Christopher Pearson, Michael C Petty

Affiliation

¹ School of Chemistry, University of St Andrews, Centre for Biomolecular Sciences, Haugh, North St Andrews, Fife, UK KY16 9ST.

PMID: 12109094
DOI: 10.1039/b202891c

Abstract

(+/-)-Erythro- and (+/-)-threo-9,10-difluorostearic acids, which differ only by a stereogenic interconversion of a single C-F bond, have significantly different conformational stabilities.