[Clomiphene--its use from stimulation test and for treatment of functional sterility]

Zentralbl Gynakol. 1975;97(23):1450-7.
[Article in German]

Abstract

There is reported on application of clomiphene (Clostilbegyt-EGYT Pharmaceutical Works, Budapest, Hungaria) in 17 patients for a clomiphene-stimulation-test and in 34 patients with functional sterility on 124 cycles. The dosage was between 50 to 150 mg p.d. for 5 to 7 days and was adapted individually. 12 patients responded to clomiphene-stimulation-test positively and in 4 ovarian hypoplasias and one Anorexia nervosa in acute phase, the clomiphene-stimulation-test was negatively. From the 34 patients with functional sterility 18 women were in 21 times gravid, 13 women could be delivered on term; in 8 cases it was an abortion. By reason of the findings after a clomiphene therapy a gravidity can be accepted, if the hyperthermic phase in the BBT existed for more than 25 days. For a repetition - treatment a dosage is recommended with 150 mg p.d. clomiphene for 7 days.

Publication types

  • English Abstract

MeSH terms

  • Adult
  • Amenorrhea / drug therapy
  • Clomiphene / administration & dosage
  • Clomiphene / pharmacology
  • Clomiphene / therapeutic use*
  • Female
  • Humans
  • Infertility, Female / drug therapy*
  • Ovulation / drug effects
  • Polycystic Ovary Syndrome / drug therapy
  • Pregnancy

Substances

  • Clomiphene