HFE gene mutations prevent sustained virological response to interferon plus ribavirin in chronic hepatitis C patients with serum markers of iron overload

Am J Gastroenterol. 2002 Jun;97(6):1570-2. doi: 10.1111/j.1572-0241.2002.05753.x.
No abstract available

Publication types

  • Letter

MeSH terms

  • Adult
  • Antiviral Agents / therapeutic use*
  • Biomarkers / blood
  • Drug Therapy, Combination
  • Female
  • HLA Antigens / genetics*
  • Hemochromatosis Protein
  • Hepacivirus / drug effects
  • Hepatitis C, Chronic / blood
  • Hepatitis C, Chronic / complications
  • Hepatitis C, Chronic / drug therapy*
  • Hepatitis C, Chronic / genetics*
  • Histocompatibility Antigens Class I / genetics*
  • Humans
  • Interferons / therapeutic use*
  • Iron Overload / blood
  • Iron Overload / complications*
  • Male
  • Membrane Proteins*
  • Middle Aged
  • Mutation / physiology*
  • Ribavirin / therapeutic use*

Substances

  • Antiviral Agents
  • Biomarkers
  • HFE protein, human
  • HLA Antigens
  • Hemochromatosis Protein
  • Histocompatibility Antigens Class I
  • Membrane Proteins
  • Ribavirin
  • Interferons