Views of transcription initiation

Brian A Young; Tanja M Gruber; Carol A Gross

doi:10.1016/s0092-8674(02)00752-3

Views of transcription initiation

Cell. 2002 May 17;109(4):417-20. doi: 10.1016/s0092-8674(02)00752-3.

Authors

Brian A Young¹, Tanja M Gruber, Carol A Gross

Affiliation

¹ Department of Biochemistry and Biophysics, University of California, San Francisco, 94143, USA.

PMID: 12086598
DOI: 10.1016/s0092-8674(02)00752-3

Abstract

Initiation of transcription is the first step in gene expression and a major point of regulation. Recent structural studies reveal the nature of the initiating complex and suggest new ways of accomplishing the processes required for initiation.

Publication types

Review

MeSH terms

Animals
DNA-Directed RNA Polymerases / genetics*
Gene Expression Regulation, Bacterial / genetics
Humans
Molecular Structure
Promoter Regions, Genetic / genetics
Protein Structure, Tertiary / genetics
RNA, Messenger / biosynthesis*
RNA, Messenger / genetics*
Transcription Initiation Site / physiology*
Transcription, Genetic / genetics*

Substances

RNA, Messenger
DNA-Directed RNA Polymerases