This is a hospital based retrospective study that determines the prevalence of pulmonary tuberculosis (PTB) and seroprevalence of Human Immunodeficiency Virus (HIV) infection amongst PTB cases. The study was over a nine year period. The annual distribution of all PTB and PTB/HIV co-infected cases were estimated, so was the annual distribution of all medical cases seen over the same period. A total of 104,240 medical cases were seen, out of which 9697 were confirmed PTB. This gives a prevalence rate of 9.2%. Their sex ratio was M:F 1.3:1 and about 81.6% of them were between 15-54 years of age. Only 189 out of 1496 cases of PTB screened for HIV antibody were seropositive giving a seroprevalence rate of 12.6%. The annual distribution of PTB/HIV co-infection showed a rising trend from only one case in 1991 to 20 cases in 1999. Majority of those who were seropositive were traders, housewives and drivers.