Insecticide treated curtains and allelic polymorphism of Plasmodium falciparum genes in a rural area of Burkina Faso (west Africa)

Parassitologia. 2001 Dec:43 Suppl 1:7-10.

Abstract

To assess the possible impact of insecticide treated curtains (ITC) on the composition of a Plasmodium falciparum population in a rural area of Burkina Faso, blood samples were collected during the rainy season of 1997 from 226 children aged 3-6 years, from 4 villages equipped with ITC and 2 control villages without ITC. The analysis of fragment lengths of 3 highly polymorphic P. falciparum genes (msp-1, msp-2 and glurp) revealed a maximum number of 3 alleles per infected person for each gene. The mean number of clones per infected person was similar in villages with and without ITC.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alleles*
  • Animals
  • Antigens, Protozoan / genetics
  • Bedding and Linens / parasitology*
  • Burkina Faso
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Insecticides / pharmacology*
  • Male
  • Merozoite Surface Protein 1 / genetics
  • Plasmodium falciparum / drug effects
  • Plasmodium falciparum / genetics*
  • Polymorphism, Genetic / drug effects*
  • Protozoan Proteins / genetics
  • Rural Health
  • Seasons

Substances

  • Antigens, Protozoan
  • Insecticides
  • Merozoite Surface Protein 1
  • Protozoan Proteins
  • merozoite surface protein 2, Plasmodium
  • glutamate-rich protein, Plasmodium