Biomedicine. D-Day for BRCA2

Science. 2002 Jul 26;297(5581):534. doi: 10.1126/science.1074482. Epub 2002 Jun 13.

Authors

Emily Witt¹, Alan Ashworth

Affiliation

¹ The Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London SW3 6JB, UK. elisa@icr.ac.uk

PMID: 12065747
DOI: 10.1126/science.1074482

No abstract available

Publication types

Comment

MeSH terms

Animals
Ataxia Telangiectasia Mutated Proteins
BRCA1 Protein / metabolism
BRCA2 Protein / metabolism
Breast Neoplasms / genetics*
Cell Cycle Proteins
DNA Damage
DNA Repair
DNA-Binding Proteins
Fanconi Anemia / genetics*
Fanconi Anemia Complementation Group D2 Protein
Genes, BRCA2*
Genetic Predisposition to Disease
Heterozygote
Homozygote
Humans
Mice
Mice, Knockout
Mutation
Nuclear Proteins / genetics
Nuclear Proteins / metabolism
Phenotype
Protein Serine-Threonine Kinases / metabolism
Tumor Suppressor Proteins

Substances

BRCA1 Protein
BRCA2 Protein
Cell Cycle Proteins
DNA-Binding Proteins
FANCD2 protein, human
Fancd2 protein, mouse
Fanconi Anemia Complementation Group D2 Protein
Nuclear Proteins
Tumor Suppressor Proteins
ATM protein, human
Ataxia Telangiectasia Mutated Proteins
Atm protein, mouse
Protein Serine-Threonine Kinases