The 3D's of apoptosis: death, degradation and DIAPs

Tanapat Palaga; Barbara Osborne

doi:10.1038/ncb0602-e149

The 3D's of apoptosis: death, degradation and DIAPs

Nat Cell Biol. 2002 Jun;4(6):E149-51. doi: 10.1038/ncb0602-e149.

Authors

Tanapat Palaga¹, Barbara Osborne

Affiliation

¹ Department of Microbiology, University of Massachusetts, Amherst, MA 01003, USA.

PMID: 12042828
DOI: 10.1038/ncb0602-e149

Abstract

Inhibitor of apoptosis proteins (IAPs) are critical regulators of apoptosis. Recent evidence suggests that in some situations, induction of apoptosis initiates general repression of translation, as well as the targeted ubiquitination and degradation of IAPs.

Publication types

News

MeSH terms

Animals
Apoptosis / physiology*
Drosophila Proteins / metabolism*
Inhibitor of Apoptosis Proteins
Protein Biosynthesis / physiology*
Ubiquitin / metabolism

Substances

DIAP1 protein, Drosophila
Drosophila Proteins
Inhibitor of Apoptosis Proteins
Ubiquitin