Abstract
Aspergillus flavus causes invasive external otitis associated with severe infection of the skull base. A combination of amphotericin B, surgical debridement and long-term itraconazole is considered the therapy of choice. We report a case of invasive external otitis due to A. flavus that was treated successfully with a short course of amphotericin B and long-term oral itraconazole without surgical intervention.
MeSH terms
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Administration, Oral
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Antifungal Agents / administration & dosage
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Antifungal Agents / therapeutic use
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Aspergillus flavus / isolation & purification*
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Child
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Humans
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Immunocompromised Host
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Itraconazole / administration & dosage
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Itraconazole / therapeutic use*
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Male
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Mycoses / complications
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Mycoses / drug therapy*
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Mycoses / microbiology*
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Neutropenia / complications*
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Neutropenia / microbiology
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Otitis Externa / complications
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Otitis Externa / drug therapy*
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Otitis Externa / microbiology*
Substances
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Antifungal Agents
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Itraconazole