Myrsinoic acids B, C and F, anti-inflammatory compounds from Myrsine seguinii

Biosci Biotechnol Biochem. 2002 Mar;66(3):655-9. doi: 10.1271/bbb.66.655.

Abstract

The methanolic extract of Myrsine seguinii yielded three anti-inflammatory compounds, myrsinoic acids B, C and F, and their structures were elucidated from the spectroscopic data. These compounds suppressed the TPA-induced edema of mouse ear, myrsinoic acid F being the most active (IE 77% at a dose of 0.56 micromol).

MeSH terms

  • Alkenes / chemistry*
  • Alkenes / isolation & purification
  • Alkenes / pharmacology*
  • Animals
  • Anti-Inflammatory Agents, Non-Steroidal / chemistry*
  • Anti-Inflammatory Agents, Non-Steroidal / isolation & purification
  • Anti-Inflammatory Agents, Non-Steroidal / pharmacology*
  • Benzofurans / chemistry*
  • Benzofurans / isolation & purification
  • Benzofurans / pharmacology*
  • Chromans / chemistry*
  • Chromans / isolation & purification
  • Chromans / pharmacology*
  • Magnetic Resonance Spectroscopy
  • Mass Spectrometry
  • Mice
  • Plant Extracts / chemistry
  • Plant Leaves / chemistry
  • Plant Stems / chemistry
  • Plants, Medicinal / chemistry*
  • Primulaceae / chemistry*
  • Spectrophotometry, Infrared

Substances

  • Alkenes
  • Anti-Inflammatory Agents, Non-Steroidal
  • Benzofurans
  • Chromans
  • Plant Extracts
  • myrsinoic acid B
  • myrsinoic acid C
  • myrsinoic acid F