Abstract
The methanolic extract of Myrsine seguinii yielded three anti-inflammatory compounds, myrsinoic acids B, C and F, and their structures were elucidated from the spectroscopic data. These compounds suppressed the TPA-induced edema of mouse ear, myrsinoic acid F being the most active (IE 77% at a dose of 0.56 micromol).
MeSH terms
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Alkenes / chemistry*
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Alkenes / isolation & purification
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Alkenes / pharmacology*
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Animals
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Anti-Inflammatory Agents, Non-Steroidal / chemistry*
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Anti-Inflammatory Agents, Non-Steroidal / isolation & purification
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Anti-Inflammatory Agents, Non-Steroidal / pharmacology*
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Benzofurans / chemistry*
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Benzofurans / isolation & purification
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Benzofurans / pharmacology*
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Chromans / chemistry*
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Chromans / isolation & purification
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Chromans / pharmacology*
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Magnetic Resonance Spectroscopy
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Mass Spectrometry
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Mice
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Plant Extracts / chemistry
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Plant Leaves / chemistry
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Plant Stems / chemistry
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Plants, Medicinal / chemistry*
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Primulaceae / chemistry*
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Spectrophotometry, Infrared
Substances
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Alkenes
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Anti-Inflammatory Agents, Non-Steroidal
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Benzofurans
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Chromans
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Plant Extracts
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myrsinoic acid B
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myrsinoic acid C
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myrsinoic acid F