Reproduction life history and hip fractures

Ann Epidemiol. 2002 May;12(4):257-63. doi: 10.1016/s1047-2797(01)00275-7.

Abstract

Purpose: The present study assesses the association between reproduction and hip fractures.

Methods: We used two surveys on elderly Danish twins of both sexes and the Danish National Register of Patients. In a cross-sectional study of 2045 twins aged 75-98 years in 1995, we studied the association between different aspects of reproduction and hip fractures leading to hospitalization between 1977 and 1994. In a prospective study, 3057 twins aged 66-99 years in 1977 were followed for a total of 29,112 years, and the association between number of children and incidence of hip fractures was investigated.

Results: In the cross-sectional study, as well as the prospective study, we found, for both sexes, that having no children was associated with a higher risk of hip fracture compared to having at least one child. When excluding persons without children, we found no effect of number of birth events/children. In the cross-sectional study, we found no effect of birth interval length or age at first birth. For women, we found an effect of age at last birth.

Conclusions: No "cost-of-reproduction" in terms of hip fractures was observed. On the contrary, we found that having one or more children was associated with a lower risk of hip fracture.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Cross-Sectional Studies
  • Denmark / epidemiology
  • Female
  • Hip Fractures / epidemiology*
  • Humans
  • Male
  • Parity
  • Pregnancy
  • Prospective Studies
  • Reproductive History*
  • Risk Factors