Research shows that older adults use memory strategies as a compensatory mechanism for coping with age-related memory loss. This research investigated the type of memory strategies used by older adults living independently in the community in adhering to their prescription medications. Older adults reported greater use of internal memory strategies and a preference for event-based over time-based prescription medication instructions. Depression and memory anxiety were significant predictors of type of medication adherence strategies used among the elderly. Health status and social support were not major determinants of the type of medication adherence strategy used.