Abstract
The title compound, C(20)H(21)NO(3), is a derivative of Aib (alpha-aminoisobutyric acid) and is cyclized at the C(alpha) position by biphenyl rings. The seven-membered ring possesses C2 symmetry. The C(alpha) cyclization causes the backbone to assume a helical conformation in the crystal structure. The packing of the molecules is stabilized by intermolecular C-H.O, C-H.pi and N-H.O hydrogen bonds.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Crystallography, X-Ray
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Cycloheptanes / chemical synthesis
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Cycloheptanes / chemistry*
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Esters / chemical synthesis
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Esters / chemistry*
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Glycine / analogs & derivatives*
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Glycine / chemical synthesis
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Glycine / chemistry*
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Models, Molecular
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Molecular Conformation
Substances
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Cycloheptanes
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Esters
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ethyl 6-acetylamino-6,7-dihydro-5H-dibenzo(a,c)cycloheptene-6-carboxylate
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Glycine