IL12B polymorphism and type 1 diabetes in the Italian population: a case-control study

Diabetes. 2002 May;51(5):1649-50. doi: 10.2337/diabetes.51.5.1649.

Abstract

A polymorphism in the interleukin 12B gene was recently reported to be strongly associated with type 1 diabetes in 422 Australian and British families. We analyzed the same polymorphism in 470 Italian type 1 diabetic patients and 544 matched control subjects and found no evidence of association with the disease.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Case-Control Studies
  • Child
  • Diabetes Mellitus, Type 1 / epidemiology
  • Diabetes Mellitus, Type 1 / genetics*
  • Female
  • Gene Frequency
  • Genetic Predisposition to Disease
  • Haplotypes
  • Humans
  • Interleukin-12 / genetics*
  • Italy / epidemiology
  • Male
  • Polymorphism, Genetic*
  • Risk Factors

Substances

  • Interleukin-12

Grants and funding