Crossover interference in Arabidopsis

Genetics. 2002 Apr;160(4):1631-9. doi: 10.1093/genetics/160.4.1631.

Abstract

The crossover distribution in meiotic tetrads of Arabidopsis thaliana differs from those previously described for Drosophila and Neurospora. Whereas a chi-square distribution with an even number of degrees of freedom provides a good fit for the latter organisms, the fit for Arabidopsis was substantially improved by assuming an additional set of crossovers sprinkled, at random, among those distributed as per chi square. This result is compatible with the view that Arabidopsis has two pathways for meiotic crossing over, only one of which is subject to interference. The results further suggest that Arabidopsis meiosis has >10 times as many double-strand breaks as crossovers.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Arabidopsis / genetics*
  • Arabidopsis Proteins
  • Cell Cycle Proteins*
  • Crossing Over, Genetic*
  • DNA-Binding Proteins / metabolism
  • Genetic Markers
  • Likelihood Functions
  • Rec A Recombinases

Substances

  • Arabidopsis Proteins
  • Cell Cycle Proteins
  • DNA-Binding Proteins
  • Genetic Markers
  • ATDMC1 protein, Arabidopsis
  • Rec A Recombinases