Comparison between the role of discontinuities in cardiac conduction and in a one-dimensional hardware model

M deCastro; E Hofer; A P Muñuzuri; M Gómez-Gesteira; G Plank; I Schafferhofer; V Pérez-Muñuzuri; V Pérez-Villar

doi:10.1103/physreve.59.5962

Comparison between the role of discontinuities in cardiac conduction and in a one-dimensional hardware model

Phys Rev E Stat Phys Plasmas Fluids Relat Interdiscip Topics. 1999 May;59(5 Pt B):5962-9. doi: 10.1103/physreve.59.5962.

Authors

M deCastro¹, E Hofer, A P Muñuzuri, M Gómez-Gesteira, G Plank, I Schafferhofer, V Pérez-Muñuzuri, V Pérez-Villar

Affiliation

¹ Grupo de Fisica No Lineal, Facultad de Fisica, Universidad Santiago de Compostela, 15706 Santiago de Compostela, Spain. uscfmmcr@cesga.es

PMID: 11969578
DOI: 10.1103/physreve.59.5962

Abstract

In real electrophysiological experiments, irregularities in the extracellular excitation spread are believed to depend on cardiac tissue microstructure. An electronic hardware model was developed to analyze this dependence by placing some inhomogeneities (slow propagation areas) in the medium. The position of such inhomogeneities is correlated with abnormal delays and irregularities measured in signal propagation.

Publication types

Comparative Study
Research Support, Non-U.S. Gov't

MeSH terms

Animals
Biophysical Phenomena
Biophysics
Electrophysiology
Guinea Pigs
Heart Conduction System / physiology*
In Vitro Techniques
Models, Cardiovascular*
Signal Transduction