Site-specific recombination with the chromosomal tRNA(Leu) gene by the large conjugative Haemophilus resistance plasmid

Antimicrob Agents Chemother. 2002 May;46(5):1602-3. doi: 10.1128/AAC.46.5.1602-1603.2002.

Abstract

Characterization of the sequences involved in recombination of the Haemophilus plasmid p1056 with the Haemophilus influenzae chromosome produced evidence indicating site-specific recombination with chromosomal tRNA(Leu). attP sequences identical to those of p1056 were found in six plasmids of diverse origin, suggesting that a family of Haemophilus plasmids recombines with chromosomal tRNA(Leu).

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bacteriophages / genetics
  • Chromosomes, Bacterial*
  • Cloning, Molecular
  • Conjugation, Genetic*
  • Drug Resistance, Bacterial / genetics
  • Haemophilus influenzae / drug effects*
  • Haemophilus influenzae / genetics
  • Haemophilus influenzae / virology
  • Humans
  • Molecular Sequence Data
  • Plasmids / genetics*
  • RNA, Transfer, Leu / genetics*
  • Recombination, Genetic*
  • Sequence Analysis, DNA

Substances

  • RNA, Transfer, Leu

Associated data

  • GENBANK/AF467800
  • GENBANK/AF467995
  • GENBANK/U68467