In vitro characterization and in vivo properties of a carbonated apatite bone cement

J Biomed Mater Res. 2002 Jun 15;60(4):633-42. doi: 10.1002/jbm.10132.

Abstract

This study evaluated the in vivo behavior of an injectable calcium phosphate bone cement implanted in bone defects at the distal end of rabbit femora. After 3 weeks, samples were harvested and processed for undecalcified sectioning. Scanning electron microscopy, transmission electron microscopy, and Fourier transform infrared microspectroscopy showed direct contact of bone and cement without soft tissue interposition, biocompatibility, and bioactivity with osteoconductive properties.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Apatites / chemistry*
  • Biocompatible Materials / chemistry
  • Bone Cements / chemistry*
  • Bone Regeneration*
  • Carbon / chemistry*
  • Femur / ultrastructure
  • Rabbits
  • Spectroscopy, Fourier Transform Infrared
  • Time Factors

Substances

  • Apatites
  • Biocompatible Materials
  • Bone Cements
  • Carbon