Electric current density imaging of tablet dissolution

Cell Mol Biol Lett. 2002;7(1):136-8.

Abstract

The Electric current density imaging technique (CDI) was used to monitor the dissolution of and ion migration from tablets of different acids in agar-agar gel. Conventional MRI cannot monitor these processes, since it can only show changes in the size of the tablet during the dissolving process. CDI traces the dissolved ions thanks to changes in conductivity.

MeSH terms

  • Electricity
  • Magnetic Resonance Imaging / methods*
  • Solubility
  • Solutions / analysis
  • Solutions / chemistry
  • Tablets / chemistry*
  • Technology, Pharmaceutical / methods*
  • Time Factors

Substances

  • Solutions
  • Tablets