Not just research tools--proteasome inhibitors offer therapeutic promise

Nat Med. 2002 Apr;8(4):338-40. doi: 10.1038/nm0402-338.
No abstract available

Publication types

  • News

MeSH terms

  • Animals
  • Cell Division / drug effects
  • Cysteine Endopeptidases
  • Humans
  • Inflammation / drug therapy
  • Mice
  • Models, Molecular
  • Multienzyme Complexes / antagonists & inhibitors*
  • Neoplasms / drug therapy
  • Peptide Hydrolases / chemistry
  • Protease Inhibitors / therapeutic use*
  • Proteasome Endopeptidase Complex
  • Protein Conformation
  • Psoriasis / drug therapy
  • Psoriasis / pathology

Substances

  • Multienzyme Complexes
  • Protease Inhibitors
  • Peptide Hydrolases
  • Cysteine Endopeptidases
  • Proteasome Endopeptidase Complex
  • ATP dependent 26S protease