Abstract
Objective:
To select the optimal technological process for Suanzaoren decoction.
Method:
The effects of extracts from different technological processes on spontaneous motion and sleep time in mice induced by pentobarbital sodium (subthreshold dosage) were studied.
Results:
Both the decoction and 95% alcohol extract of Suanzaoren possess sedative and hypnotic effects.
Conclusion:
Suanzaoren aqueous decoction was selected as the optimal technological process.
MeSH terms
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Animals
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Drug Combinations
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Drugs, Chinese Herbal / isolation & purification
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Drugs, Chinese Herbal / pharmacology*
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Female
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Fruit / chemistry
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Hypnotics and Sedatives / pharmacology
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Male
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Mice
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Motor Activity / drug effects
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Plant Extracts / isolation & purification
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Plant Extracts / pharmacokinetics*
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Sleep / drug effects
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Technology, Pharmaceutical / methods*
Substances
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Drug Combinations
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Drugs, Chinese Herbal
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Hypnotics and Sedatives
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Plant Extracts
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suanzaorentang