Treatment of canine atopic dermatitis with zafirlukast, a leukotriene-receptor antagonist: a single-blinded, placebo-controlled study

Can Vet J. 2002 Mar;43(3):203-6.

Abstract

Zafirlukast and placebo were administered orally as individual agents to 20 dogs with atopic dermatitis. The pruritus was effectively reduced by at least 50% in 2/18 (11%) dogs that completed the trial with zafirlukast. Two dogs vomited after administration of the active drug.

Publication types

  • Clinical Trial
  • Controlled Clinical Trial

MeSH terms

  • Administration, Oral
  • Animals
  • Cross-Over Studies
  • Dermatitis, Atopic / drug therapy
  • Dermatitis, Atopic / veterinary*
  • Dog Diseases / drug therapy*
  • Dogs
  • Female
  • Indoles
  • Leukotriene Antagonists / therapeutic use*
  • Male
  • Phenylcarbamates
  • Single-Blind Method
  • Sulfonamides
  • Tosyl Compounds / therapeutic use*
  • Treatment Outcome

Substances

  • Indoles
  • Leukotriene Antagonists
  • Phenylcarbamates
  • Sulfonamides
  • Tosyl Compounds
  • zafirlukast