3,4-Dihydro-6-methyl-3-beta-D-ribofuranosyl-4,5'-cyclo-9H-imidazo[1,2-a]purin-9-one hydrate

Acta Crystallogr C. 2002 Mar;58(Pt 3):o133-5. doi: 10.1107/s0108270101021904. Epub 2002 Feb 13.

Abstract

In the title compound, C(13)H(13)N(5)O(4) x H(2)O (4,5'-cyclowyosine x H(2)O), the cyclization forces a syn arrangement of the aglycon with respect to the sugar moiety. The ribofuranose part of the molecule displays a beta-D configuration with an envelope C1'-endo pucker. The molecules are arranged in columns along the short a axis and are linked to water molecules through O-H...O and O-H...N hydrogen bonds.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Crystallography, X-Ray
  • Hydrogen Bonding
  • Imidazoles / chemistry*
  • Models, Molecular
  • Molecular Conformation
  • Nucleosides / chemistry*
  • Purine Nucleosides / chemistry*

Substances

  • 4,5'-cyclowyosine
  • Imidazoles
  • Nucleosides
  • Purine Nucleosides