In-vitro study of bacterial adherence to different types of intraocular lenses

Drug Dev Ind Pharm. 2002 Jan;28(1):95-9. doi: 10.1081/ddc-120001490.

Abstract

The aim of this study was to determine the adherence of Staphylococcus epidermidis to intraocular lenses made of five different biomaterials: polymethylmethacrylate (PMMA), heparinized PMMA, silicone, hydrophilic acrylic, and hydrogel. The extent of bacterial binding was measured by counting. The results were compared using a one-factor variance analysis. Adherence was weakest on hydrogel and strongest on the silicone polymer. Bacterial adherence to the implant surface must therefore depend on the hydrophobicity or hydrophilicity of the biomaterial.

MeSH terms

  • Acrylates / chemistry
  • Bacterial Adhesion / physiology*
  • Biocompatible Materials / chemistry*
  • Colony Count, Microbial
  • Equipment Contamination
  • Hydrogel, Polyethylene Glycol Dimethacrylate / chemistry
  • Lenses, Intraocular / microbiology*
  • Polymers / chemistry
  • Polymethyl Methacrylate / chemistry
  • Silicon / chemistry
  • Staphylococcus epidermidis / isolation & purification
  • Staphylococcus epidermidis / physiology*

Substances

  • Acrylates
  • Biocompatible Materials
  • Polymers
  • Hydrogel, Polyethylene Glycol Dimethacrylate
  • Polymethyl Methacrylate
  • Silicon