Treatment of steroid-resistant idiopathic thrombocytopenic purpura in pregnancy with repeated high-dose intravenous immunoglobulin

Haematologia (Budap). 2001;31(3):263-5. doi: 10.1163/15685590152763827.

Abstract

High-dose intravenous immunoglobulin (HD-IVIG) has temporary but reliable efficacy in idiopathic thrombocytopenic purpura (ITP). HD-IVIG has been described as the representative management in pregnant cases of refractory to corticosteroid or immunosuppressants. There have been few cases treated with repeated HD-IVIG to sustain pregnancy from the early phase of pregnancy. This case report describes a pregnant case of steroid-refractory ITP, treated with six times repeated HD-IVIG, resulting in the successful delivery of a healthy newborn with a normal platelet count. No adverse effects were observed.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Cesarean Section
  • Chronic Disease
  • Drug Resistance
  • Female
  • Humans
  • Immunoglobulins, Intravenous / administration & dosage*
  • Pregnancy
  • Pregnancy Complications, Hematologic / drug therapy*
  • Pregnancy Outcome
  • Purpura, Thrombocytopenic, Idiopathic / drug therapy*
  • Steroids

Substances

  • Immunoglobulins, Intravenous
  • Steroids