Chronic myelomonocytic leukemia has been associated with various nonspecific cutaneous manifestations. Rarely has the leucaemia been reported to directly affect the skin. We present a case of 53-year old man with CMML who showed neoplastic cutaneous lesions. The occurrence of these lesions may be the presenting feature of the disease or may herald its progression to acute leukemia. Early diagnosis have therapeutic and prognostic significance.