In vitro and in silico analysis of the predicted human MOB gene encoding a phylogenetically conserved transmembrane protein

I P Vladychenskaya; L V Dergunova; S A Limborska

doi:10.1016/s1389-0344(01)00110-1

In vitro and in silico analysis of the predicted human MOB gene encoding a phylogenetically conserved transmembrane protein

Biomol Eng. 2002 Feb;18(6):263-8. doi: 10.1016/s1389-0344(01)00110-1.

Authors

I P Vladychenskaya¹, L V Dergunova, S A Limborska

Affiliation

¹ Department of Human Molecular Genetics, Institute of Molecular Genetics, Russian Academy of Sciences, Kurchatov sq., 2, 123182, Moscow, Russia. irinavl@img.ras.ru

PMID: 11841947
DOI: 10.1016/s1389-0344(01)00110-1

Abstract

A novel evolutionary conserved human MOB gene of seven exons is predicted on the chromosome 10. MOB is supposed to express predominately in brain. At least three types of MOB transcripts are proposed. A protein encoded by MOB is five-pass transmembrane molecule.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Amino Acid Sequence
Animals
Blotting, Northern
Chromosome Mapping
Chromosomes, Human, Pair 10 / genetics*
Cloning, Molecular
Conserved Sequence / genetics
Contig Mapping
DNA, Complementary
Exons / genetics
Humans
In Vitro Techniques
Medulla Oblongata / physiology*
Membrane Proteins / chemistry
Membrane Proteins / genetics*
Mice
Molecular Sequence Data
Nerve Tissue Proteins*
Pattern Recognition, Automated
Phylogeny
Sequence Analysis, DNA
Transferases (Other Substituted Phosphate Groups)

Substances

DNA, Complementary
Membrane Proteins
Nerve Tissue Proteins
SGMS1 protein, human
Transferases (Other Substituted Phosphate Groups)

Associated data

GENBANK/AK026683
GENBANK/Y14155