Virulence factors of clinical isolates of Aeromonas caviae

Folia Microbiol (Praha). 2001;46(4):321-6. doi: 10.1007/BF02815621.

Abstract

The mechanism of pathogenicity of 13 Aeromonas caviae strains isolated from fecal specimens of children with diarrhea was examined. Isolates possessed several virulence agents. Six of 13 isolates produced cholera-like toxin, all strains exhibited adhesive ability and secreted catecholate siderophores. Six isolates were able to grow in heat-inactivated serum. Production of hemolysins was not detected. The isolates had relatively high values of LD50 in a mouse model, which suggests that there is no linkage between pathogenicity to mice and the diarrheagenic ability of the isolates.

MeSH terms

  • Aeromonas / growth & development
  • Aeromonas / isolation & purification
  • Aeromonas / pathogenicity*
  • Animals
  • Bacterial Adhesion
  • Bacterial Toxins / biosynthesis
  • Bacterial Toxins / immunology
  • Child
  • Cholera Toxin / immunology
  • Culture Media
  • Diarrhea / microbiology*
  • Disease Models, Animal
  • Feces / microbiology
  • Gram-Negative Bacterial Infections / microbiology*
  • Humans
  • Jejunum / microbiology
  • Lethal Dose 50
  • Mice
  • Rabbits
  • Siderophores
  • Virulence

Substances

  • Bacterial Toxins
  • Culture Media
  • Siderophores
  • Cholera Toxin