[Treating portal hypertension by subtotal splenectomy with retroperitoneal splenic transposition and devascularization: clinical study]

Zhonghua Wai Ke Za Zhi. 1998 Jun;36(6):333-5, 71.
[Article in Chinese]

Abstract

Objective: To devise a new surgical procedure for improving the operative effect of portal hypertension caused by hepatic cirrhosis.

Method: In treatment group, subtotal splenectomy with retroperitoneal transposition was performed in 36 patients of cirrhotic hypertensives. In control group, 36 patients were treated by devascularization. The follow-up period ranged from 3 months to 5.5 years (average 26 months).

Result: In the treatment group, the rates of disappearance, improvement and absence of changes of esophageal varices were 11.5%, 61.5% and 26.9%, respectively, and in the control group those of improvement were 50.0%, absence of change 45.8% and aggravation 4.2%. There was a significant difference between them (P < 0.05). In the treatment group, hypersplenism disappeared in all. There was also significant difference between the two groups in immunological indexes (P < 0.05). DSA showed abundant collateral circulation in the residual spleen and retroperitoneal wall, which enabled the portal blood flow diverting to retroperitoneal tissues.

Conclusion: This method possesses the advantages of devascularization and decompression shunt. It is of value in retaining part of spleen in surgical treatment of portal hypertension.

Publication types

  • Clinical Trial
  • English Abstract
  • Randomized Controlled Trial

MeSH terms

  • Female
  • Follow-Up Studies
  • Humans
  • Hypertension, Portal / surgery*
  • Liver Cirrhosis / complications*
  • Male
  • Splenectomy / methods*
  • Splenorenal Shunt, Surgical / methods*