Objective: To investigate the effect decreasing of the incidence of endodontic interappointment pain(EIP) by local injection of 5 mg dexamethasone.
Methods: 5 mg dexamethasone was injected submucosally at apical region of 80 teeth with asymtomatic pulp necrosis after root canal therapy, then observing the incidence of EIP and compared with control group.
Results: The clinical observation revealed that the incidence of EIP of dexamethasone group (10.00%) was lower than that of control group (33.75%), P < 0.01, and the level of pain was decreased. Ordinal logistic regression revealed that EIP was related to tooth location, fistula, and root canal therapy.
Conclusion: The incidence of EIP can be reduced after 5 mg dexamethasone local injected.