[Epidemiological characteristics of a group of multi organ donors used to transplant organs in Cuba]

Rev Neurol. 2001 Dec;33(12):1117-9.
[Article in Spanish]

Abstract

Introduction: For current transplants, the organ donor is a basic factor.

Objectives: To determine the demographic characteristics of the donors used in the Cuban liver transplant programme, the main causes of brain death, most widely used amines and serology pattern. To report the transplants carried out.

Patients and methods: We reviewed the clinical histories of the actual donors processed between July 1999 and July 2000.

Results: During the period studied 13 actual donors were used: 9 men (69.2%) and 4 women (30.8%) distributed in the following age groups: 15 30 years: 3 cases (23%); 31 45 years : 4 cases (30.8%); 46 60 years: 5 cases (38.5%), and over 60 years: 1 case (7.7%). We did 42 transplants: 12 liver, including the first hepato renal in Cuba, 18 kidney, 10 cornea, and 1 heart. The causes of death were: head injury: 10 (76.9%), and hemorrhagic cerebral vascular accident: 3 (23.1%). Only 3 cases (23.1%) did not require the use of vasoactive amines. These were used in the other 10 (76.9%). The most commonly used were dopamine and epinephrine, in 6 cases each (46.1%). In the serological studies for immunoglobulin G for cytomegalovirus all 13 were positive, Epstein Barr virus 6 (46.1%), toxoplasma 12 (92.3%), herpes virus 1: 13, herpes virus 11: 13.

Conclusions: The typical donor was a man aged 46 60 years with brain death due to head injury following a road traffic accident. A large proportion of donors required the use of amines to maintain hemodynamic stability. There was a large proportion of patients who were found on microbiological serology studies to test positive.

Publication types

  • English Abstract
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Cause of Death
  • Cuba
  • Female
  • Humans
  • Male
  • Middle Aged
  • Tissue Donors*
  • Transplantation / statistics & numerical data*
  • Virus Diseases