A computational study of the hemodynamics after "edge-to-edge" mitral valve repair

J Biomech Eng. 2001 Dec;123(6):565-70. doi: 10.1115/1.1408938.

Abstract

Edge-to-edge mitral valve repair consists in suturing the free edge of the leaflets to re-establish coaptation in prolapsing valves. The leaflets are frequently sutured at the middle and a double orifice valve is created. In order to study the hemodynamic implications, a parametric model of the left heart has been developed. Different valve areas and shapes have been investigated. Results show that the simplified Bernoulli formula provides a good estimation of the pressure drop and that the pressure drop may be predicted on the basis of the pre-operative geometric and hemodynamics data by means of customized models.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Blood Flow Velocity / physiology
  • Blood Pressure
  • Computer Simulation*
  • Finite Element Analysis
  • Heart Ventricles / pathology
  • Heart Ventricles / physiopathology
  • Hemodynamics
  • Humans
  • Mitral Valve / pathology
  • Mitral Valve / physiopathology*
  • Mitral Valve / surgery*
  • Mitral Valve Prolapse / physiopathology*
  • Mitral Valve Prolapse / surgery*
  • Models, Cardiovascular*