Objective: To study the mechanism of anti-allergic effect of Xiaoqinglong Decoction (XQLD).
Methods: The influence of XQLD drug-serum frozen powder on degranulation and histamine releasing of peritoneal mastocyte in sensitized rats was examined by morphologic and fluorimetric method.
Results: The drug-serum prepared by serum obtained 2 hours after medication for 15 min has obvious inhibitory effect on degranulation and histamine releasing of peritoneal mastocyte which showed a basically unified time-effect relationship.
Conclusion: The anti-allergic effect of XQLD is related with the allergic medium (histamine) inhibition of releasing of peritoneal mastocyte.