Objective: To observe the therapeutic effect of Xialian Yiyou Capsule (XLYYC) on helicobacter pylori (HP) infected gastritis to develop the serial Chinese classical recipe.
Methods: HP infected patients were divided into two groups, 136 patients in the XLYYC group treated with XLYYC and 90 patients in the control group treated with Lizhu Dele Capsule, for 4 weeks as one therapeutic course, the clinical therapeutic effect was observed, and corresponding animal experiments were done.
Results: Clinical effect of the XLYYC group was better than that of the control group in improving clinical symptoms, relieving inflammation of gastric mucosa and eliminating HP (P < 0.05, P < 0.01). Results of animal experiment showed that XLYYC was superior than the control significantly in anti-inflammation, analgesia, stomach emptying and curing gastric ulcer model (P < 0.05, P < 0.01). Without any adverse reaction has been found in acute toxicologic study.
Conclusion: The therapeutic effect of XLYYC in treating HP infected gastritis was definite and safe, non-toxic.