Background: Collagenous colitis is a diarrheal illness of unknown cause. The purpose of this report is to describe a case of collagenous colitis related to lansoprazole exposure.
Study: Case report.
Results: A patient is described who developed clinical and pathologic findings of collagenous colitis during treatment with lansoprazole and omeprazole. Symptoms of diarrhea and histopathologic abnormalities resolved after drug withdrawal and recurred with re-exposure to lansoprazole.
Conclusions: The observations are compatible with collagenous colitis or lymphocytic colitis associated with exposure to lansoprazole.