Syntheses of anolignans A and B using ruthenium-catalyzed cross-enyne metathesis

J Org Chem. 2002 Jan 11;67(1):224-6. doi: 10.1021/jo0107913.

Abstract

Anolignans A and B were synthesized using ruthenium-catalyzed cross-enyne metathesis as the key steps. The 1,3-diene moieties of these natural products were constructed by the introduction of the methylene parts of ethylene into alkyne using Grubbs' catalyst.

MeSH terms

  • Alkynes / chemistry
  • Catalysis
  • Lignans / chemical synthesis*
  • Reverse Transcriptase Inhibitors / chemical synthesis*
  • Ruthenium / chemistry

Substances

  • Alkynes
  • Lignans
  • Reverse Transcriptase Inhibitors
  • anolignan A
  • anolignan B
  • Ruthenium