Partial left ventriculectomy and limited heart transplantation availability

J Card Surg. 2001 Mar-Apr;16(2):165-9. doi: 10.1111/j.1540-8191.2001.tb00503.x.

Abstract

Background and aim: Partial left ventriculectomy, a novel cardiac volume reduction operation, is applied in countries without a developed heart transplantation program. We sought to determine its impact in our population of patients.

Methods: Partial left ventriculectomy was performed in 38 patients during the last 4 years. Basic inclusion criteria were nonischemic dilated cardiomyopathy and poor response to medical therapy for heart failure. Hemodynamic evaluation was carried out before and after operation. A modified surgical technique of mitral valve repair and ventricle suturing was applied.

Results: Thirty-day, 6-month, and 2-year survival rates were 82% +/- 7%, 65% +/- 8%, and 61% +/- 9%, respectively. Duration of heart failure symptoms was the only predictor of survival (p = 0.042). A high proportion of noncardiac causes of death was noted. Functional capacity in surviving patients improved at every successive measurement up to 1 year postoperatively.

Conclusions: The introduction of partial left ventriculectomy in a country with limited heart transplantation availability had a great impact on the management of end-stage heart failure and may represent the only surgical option for some patients. The average cost per patient was substantially lower when compared to heart transplantation.

MeSH terms

  • Adult
  • Aged
  • Cardiac Surgical Procedures / economics
  • Cardiac Surgical Procedures / methods*
  • Cardiomyopathy, Dilated / complications
  • Female
  • Heart Failure / etiology
  • Heart Failure / physiopathology
  • Heart Failure / surgery*
  • Heart Transplantation*
  • Hemodynamics
  • Humans
  • Male
  • Middle Aged
  • Proportional Hazards Models
  • Severity of Illness Index
  • Survival Analysis
  • Treatment Outcome
  • Walking
  • Yugoslavia