New 4-methoxybenzoyl derivatives from the ascidian Polycarpa aurata

J Nat Prod. 2001 Dec;64(12):1556-8. doi: 10.1021/np000570c.

Abstract

From the hydrophilic extract of the ascidian Polycarpa aurata three new compounds, N-(4-methoxybenzoyl)-N'-methylguanidine (1), butyl 2-(4-methoxyphenyl)-2-oxoacetate (2), and 2-(4-methoxyphenyl)-N-methyl-2-oxoacetamide (3), together with the known compounds methyl 2-(4-methoxyphenyl)-2-oxoacetate (4) and 4-methoxybenzoic acid were isolated. The structures of all isolates were determined from their spectroscopic data (NMR, MS, IR, UV).

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acetamides
  • Animals
  • Australia
  • Benzamides
  • Chromatography, High Pressure Liquid
  • Chromatography, Thin Layer
  • Gas Chromatography-Mass Spectrometry
  • Hydroxybenzoate Ethers
  • Hydroxybenzoates / chemistry
  • Hydroxybenzoates / isolation & purification*
  • Mass Spectrometry
  • Methylguanidine / analogs & derivatives
  • Methylguanidine / chemistry
  • Methylguanidine / isolation & purification*
  • Molecular Structure
  • Nuclear Magnetic Resonance, Biomolecular
  • Phenyl Ethers
  • Spectrophotometry, Infrared
  • Spectrophotometry, Ultraviolet
  • Structure-Activity Relationship
  • Urochordata / chemistry*

Substances

  • 2-(4-methoxyphenyl)-N-methyl-2-oxoacetamide
  • Acetamides
  • Benzamides
  • Hydroxybenzoate Ethers
  • Hydroxybenzoates
  • N-(4-methoxybenzoyl)-N'-methylguanidine
  • Phenyl Ethers
  • butyl-2-(4-methoxyphenyl)-2-oxoacetate
  • 4-anisic acid
  • Methylguanidine