Abstract
Gram-negative bacteria secrete a variety of proteins to the cell surface and beyond, a process with many inherent difficulties. An exceptionally widespread answer to these problems is the type V (or autotransporter) secretion pathway. By exploiting the data made available by bacterial genome sequencing, we have discovered that the previously described polymorphic proteins of Chlamydia spp. resemble members of the autotransporter family, and we suggest that they follow the same secretion pathway.
Publication types
-
Research Support, Non-U.S. Gov't
-
Review
MeSH terms
-
Amino Acid Sequence
-
Animals
-
Bacterial Outer Membrane Proteins / chemistry
-
Bacterial Outer Membrane Proteins / genetics*
-
Bacterial Outer Membrane Proteins / metabolism
-
Carrier Proteins / genetics*
-
Carrier Proteins / metabolism
-
Chlamydia / chemistry
-
Chlamydia / genetics
-
Chlamydia / metabolism*
-
Genome, Bacterial
-
Humans
-
Molecular Sequence Data
-
Polymorphism, Genetic* / genetics
-
Proteobacteria / genetics
-
Proteobacteria / metabolism
Substances
-
Bacterial Outer Membrane Proteins
-
Carrier Proteins