A highly substituted germacranolide from Leontodon cichoraceus

Z Naturforsch C J Biosci. 2001 Sep-Oct;56(9-10):904-8. doi: 10.1515/znc-2001-9-1038.

Abstract

A re-investigation of subaerial parts of Leontodon cichoraceus (Ten.) Sanguin. yielded the new germacrane-type sesquiterpenoid 15-beta-D-glucopyranosyl-8-[p-(beta-D-glucopyranosyloxy)phenylacetyl]-salonitenolide. The structure was established by APCI mass spectrometry and 1D- and 2D-NMR spectroscopy. A survey by HPLC-DAD and HPLC-MS gave no signs of this compound in 23 other taxa of Leontodon.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Infective Agents / chemistry
  • Anti-Infective Agents / isolation & purification*
  • Asteraceae / chemistry*
  • Chromatography, High Pressure Liquid
  • Glycosides / chemistry
  • Glycosides / isolation & purification
  • Magnetic Resonance Spectroscopy
  • Mass Spectrometry
  • Models, Molecular
  • Molecular Conformation
  • Sesquiterpenes / chemistry
  • Sesquiterpenes / isolation & purification*
  • Sesquiterpenes, Germacrane*

Substances

  • Anti-Infective Agents
  • Glycosides
  • Sesquiterpenes
  • Sesquiterpenes, Germacrane
  • germacranolide