Abstract
A new dimeric stilbene, namely, artogomezianol (1), and the known compound andalasin A (2) were isolated from the roots of Artocarpus gomezianus. Both 1 and 2 showed moderate tyrosinase inhibitory activity with IC(50) values of 68 and 39 microM, respectively.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Chromatography
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Enzyme Inhibitors / chemistry
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Enzyme Inhibitors / isolation & purification*
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Enzyme Inhibitors / pharmacology
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Inhibitory Concentration 50
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Molecular Conformation
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Molecular Structure
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Monophenol Monooxygenase / antagonists & inhibitors*
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Moraceae / chemistry*
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Nuclear Magnetic Resonance, Biomolecular
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Plant Roots / chemistry
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Plants, Medicinal / chemistry
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Spectrophotometry, Infrared
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Spectrophotometry, Ultraviolet
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Stilbenes / chemistry
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Stilbenes / isolation & purification*
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Stilbenes / pharmacology
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Structure-Activity Relationship
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Thailand
Substances
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Enzyme Inhibitors
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Stilbenes
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andalasin A
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artogomezianol
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Monophenol Monooxygenase