4-(4-Chlorophenyl)-3,7,7-trimethyl-1-[2-(4-nitrobenzoyl)ethyl]-4,7,8,9-tetrahydro-1H-pyrazolo[3,4-b]quinolin-5(6H)-one-ethanol (1/1)

Acta Crystallogr C. 2001 Nov;57(Pt 11):1356-8. doi: 10.1107/s0108270101014913. Epub 2001 Nov 13.

Abstract

Molecules of the title compound, C(28)H(27)ClN(4)O(4).C(2)H(6)O, form a C(6) chain via an N--H...O hydrogen bond along the c axis by the operation of a c-glide plane, with N...O = 2.761 (3) A and N--H...O = 165 degrees. The molecules are further linked by a weak C--H...O interaction, with C.O = 3.344 (4) A and C--H...O = 150 degrees. Pendant hydrogen-bonded ethanol solvent molecules are attached to the chains by O--H...N hydrogen bonds, with O...N = 2.904 (3) A and O--H...N = 175 degrees.

MeSH terms

  • Antiviral Agents / chemistry*
  • Crystallography, X-Ray
  • Hydrogen Bonding
  • Models, Molecular
  • Molecular Conformation
  • Pyrazoles / chemistry*
  • Quinolines / chemistry*

Substances

  • 4-(4-chlorophenyl)-3,7,7-trimethyl-1-(2-(4-nitrobenzoyl)ethyl)-4,7,8,9-tetrahydro-1H-pyrazolo(3,4-b)quinolin-5(6H)-one-ethanol
  • Antiviral Agents
  • Pyrazoles
  • Quinolines