Intact prototype learning in schizophrenia

Schizophr Res. 2001 Dec 1;52(3):261-4. doi: 10.1016/s0920-9964(00)00092-x.

Abstract

In this study, we examined executive functions and visual prototype learning in patients with schizophrenia (n=22) and matched healthy control subjects (n=20). The patients demonstrated marked perseveration in the Wisconsin Card Sorting Test (WCST), whereas they successfully learned prototypes of dot-pattern category exemplars. These findings are against the hypothesis of a pure generalized cognitive dysfunction in schizophrenia, providing preliminary evidence for intact neocortical mechanisms related to perceptual classification functions.

Publication types

  • Clinical Trial
  • Controlled Clinical Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Analysis of Variance
  • Cerebral Cortex / physiopathology
  • Cognition Disorders / etiology*
  • Cognition Disorders / physiopathology
  • Discrimination Learning*
  • Female
  • Humans
  • Male
  • Pattern Recognition, Visual*
  • Schizophrenia / complications
  • Schizophrenia / physiopathology
  • Schizophrenic Psychology*